Search coordinators are focusing their efforts on the town of Lolodorf, 90 miles south-east of Douala where the last message from the plane was received.
The pilot had confirmed takeoff from its stopover there, with the plane having begun its journey from the Ivory Coast before flying across Africa to the Kenyan capital of Nairobi.
Local residents reported hearing an explosion last night but their claims remain unconfirmed. Bad weather and difficult terrain are hampering visibility in the estimated crash zone area, according to media reports.
Kenyan Airways says that 23 different nationalities were on board the flight, including five Britons.
Although the airline's 23-strong fleet has a good safety record, this weekend's crash is not the first for the firm. In 2000, one of its fleet crashed into the ocean after leaving the Ivory Coast. Only ten people out of 179 onboard survived.
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